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Health |
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Exercise
improves blood sugar
regulation
Glucose (blood
sugar) is the most important
fuel for the brain and
nervous system. Glucose
is broken down quickly,
which makes it an attractive
fuel during muscular
exercise. After a meal,
carbohydrates travel
from the gut into the
blood stream, which
causes an increase in
blood glucose. The pancreas
secretes the hormone
insulin, which speeds
the movement of glucose
into the cells. Overweight,
inactive people often
develop insulin resistance
as they age. This means
that it takes more insulin
than normal to reduce
blood glucose after
a meal.
Researchers from Australia
summarized how exercise
improves blood sugar
regulation. Insulin
is not necessary for
speeding the transport
of glucose into skeletal
muscle. Exercise increases
the activity of three
separate signaling pathways
that speed the movement
of glucose into the
muscle cells. This makes
it easier for other
cells in the body to
control blood sugar
and regulate insulin.
Exercise has little
direct effect on insulin
metabolism, but has
a significant indirect
effect, which makes
it have a positive influence
on carbohydrate metabolism
through out the body.
(Acta Physiologica,
192: 127-135, 2008)
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Cutting
cancer risk at the barbecue
Few things taste as
good as a barbecued steak or
burger. Unfortunately, grilling
meats produces compounds called
heterocyclic amines (HCAs) that
increase the risk of cancer.
The smoke that flares back on
the meat when the fat hits the
coals produce other cancer causing
substances called polycystic
aromatic hydrocarbons (PAH).
Scientists from the national
institutes of health (NIH) suggest
barbecuing vegetables and fruits
as an alternative.
Marinating meats also decreases
HCA production by as much as
92 percent to 99 percent. Other
cancer reducing tips include
micro waving food for 1 minute
before grilling, flipping food
often and cooking red meat medium
or rare. These measures reduce
meat temperature, which prevent
the production of cancer causing
chemicals. Cutting down on red
meat consumption may also prevent
many types of cancer. (Dekalb
Medical; press release May 12,
2008) |
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Got
the rotator cuff blues?
If you throw, hit a
tennis racket swim. Or lift
weighs hard enough and long
enough, chances are you will
develop a rotator cuff problem.
The cuff is made up of four
muscles that cause the shoulder
to rotate in and out. In the
same general area of the shoulder
you will find bursa, tendons
and ligaments, all of which
can become irritated or injured
from trauma or overuse. Initial
weakness of the cuff can lead
to bursitis, tendonitis, bone
spurs, tears and ruptures. Conservative
treatment – rest, ice, rehab
exercises and anti-inflammatory
drugs is best. However, chronic
shoulder problems may require
surgery to repair or prevent
tendon tears and ruptures. Results
of shoulder surgery to repair
tendon ruptures, tears and shoulder
impingement are very good…92
percent of patients reported
a good result two and five years
after the procedure. Experts
encourage patients to do shoulder
rehab exercises religiously
for three to six months before
resorting to surgery. (American
Journal Sports Medicine, 36:
987-993, 2008)
Are you growth hormone
deficient?
Celebrities such as
Sylvester Stallone have popularized
growth hormone (GH) supplements
as a fountain of youth. Scientific
studies and anecdotal observations
from GH users suggest that it
increases bone and muscle mass,
decreases body fat, improves
energy levels, boosts sexual
performance and tightens the
skin. Critics charge that GH
supplements are a scam and that
millions of Americans are spending
a lot of money on a drug that
could damage their health and
decreases longevity. The food
and drug administration (FDA)
has approved GH supplements
for brain-based short stature
in children, growth hormone
deficiency in adults, muscle
wasting from AIDS and several
obscure metabolic disorders.
Growth hormone deficiency is
rare and is diagnosed using
an insulin challenge test. Does
GH therapy prevent some of the
symptoms of aging in metabolically
normal adults? The evidence
is mixed. One 10years long study
from Sweden found that patients
(52 men and 35 women; average
age 44) given daily injections
of GH for 10 years (0.47mg to
0.98mg per day) increased muscle
mass, maintained body fat and
improved blood markers of general
health (cholesterol, HDL (good
cholesterol), and hemoglobin
A1c (measure of blood sugar
control) (J Clin Endocrinal
Metab, 92:1442-1445, 2007).
The study showed that middle
aged adults gained substantial
benefits from long-term growth
hormone supplementation with
minimal side effects. Other
studies found that GH increased
lean mass and decreased fat,
but did not improve strength
or power output capacity. Most
adults will not meet the criteria
for growth hormone deficiency
but might benefit from hormone
replacement therapy. We need
more research to determine if
the benefits outweigh the risks.
(Growth Hormone IGF Research,
18:116, 2008) |
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Prostate
cancer patients should
continue exercising
Regular exercise
prevents colon cancer
and some evidence
suggests that it might
prevent prostate cancer
as well. However,
a study from Duke
University Medical
Center found that
human prostate tumors
implanted in mice
grew twice as fast
in animals that ran
one-haft mile per
day compared to sedentary
animals. They also
speculated that exercises
might be a way to
speed drugs to prostate
tumors, because blood
flow to prostate cancer
cells is notoriously
slow. The researchers
caution that the circumstances
of the experiment
were different from
those in normal prostate
cancer. Also, patients
benefit from exercise
by improving cardiovascular
and metabolic health.
Prostate cancer is
an extremely slow
process in most patients,
while the benefits
of exercise occur
quickly. Men with
prostate cancer will
benefit more from
the improved quality
of life as a result
of exercise, even
though physical activity
might promote cancer
cell growth. (BBC
News April 14, 2008)
Mutants live
to be 100 years old
The key to living
100 years is to choose
your parents very
carefully. It helps
if your parents are
mutants. A study led
by Nir Barzilai from
the institute for
aging at the Albert
Einstein College of
Medicine in New York
City found that centenarians
had a gene mutation
that suppressed the
activity of IGF-1
and growth hormone
(powerful growth factors).
The study examined
nearly 400 long-living
Ashkenazi Jews and
their children and
compared them with
younger, control subjects.
The daughters of the
old people in the
study had lower levels
of IGF-1 and tended
to be 2 inches shorter
than children of the
control subjects.
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Many
older people take supplemental
growth hormone to increase
IGF-1 levels in the hope of
living longer, losing fat,
gaining muscle and improving
skin texture. Also, low levels
of IGF-1 are linked to heart
disease and diabetes. Increasing
IGF-1 in your 50s and 60s
might make you feel and look
better, but it might also
prevent you from living to
100. Low IGF-1 and GH levels
are linked to increased lifespan
in insects and small mammals.
The same might be true in
humans. (Proceedings National
Academy Sciences, 105: 3438-42,
2008)
Heavy cell phone use
linked to mouth cancer
In the old days,
when you needed to speak to
your girlfriend or wife and
were on the road, you pulled
over to the nearest gas station
and called her on a pay phone.
Those days are long gone.
People depend on cell phones
for communications, internet
access and entertainment.
Many people spend hours with
the phones glued to their
ears. An Israel study found
that heavy cell phone use
increased the risk of salivary
gland tumors by 50 percent.
Researchers compared 500 Israelis
who developed the cancer with
1300 healthy controls. Salivary
cancers are rare, but the
incidences are rising. Most
studies show no link between
cell phone use and cancer,
but heavy use of these devices
is a relatively recent phenomenon.
Cancers typically take many
years to develop, so short-term
increases in cancer rates
in cell phone users is a potentially
ominous observation. On a
positive note, a 10-year study
found no link between cell
phone usage and any kind of
cancer in 420,000 people in
Denmark. (American Journal
of Epidemiology 167: 457-467,
2008)
Urban legends about
fluid requirements
Until recently, health
experts recommended that the
average person drink eight
8-ounce glasses of water per
day. In 205, the United States
department of Agriculture
changed that and recommended
that people drink fluids when
they are thirsty. Fluid requirements
are so variable that it is
impossible to make recommendations
that are appropriate for everyone.
Physically active people can
plan for increased fluid requirements
by consuming more beverages
at mealtime. Researchers from
the University of Pennsylvania,
in a review of literature,
concluded that people should
drink more water in hot climates
or if they are physically
active. Water influences sodium
and urea elimination from
the kidneys, but it is not
clear if these effects are
beneficial. Drinking water
intake above thirst levels
does not benefit the tissues
and organs and will not “flush
out” toxins and poisons. Also,
water does not suppress appetite,
promote weight loss or improve
skin texture and appearance.
We have no evidence one way
or the other for recommending
increased water intake in
the average person. You can
get too much of a good thing.
The kidneys can only process
about 1 l (about a quart)
per hour. Drinking more than
that increases your risk of
water that increases your
risk of water intoxication,
which can be deadly. The take
home message is to drink water
when you’re going to exercise
in the heat and don’t follow
any set schedule for fluid
replacement. (Journal American
Society Nephrology, in press;
published online April 2008)
Winning increases
testosterone
I love the smell
of testosterone in the morning;
it smells like victory! Cambridge
University scientists affirmed
what researchers have known
for more than 50 year: winning
increases testosterone levels.
Saliva testosterone increased
in stock traders when they
were making money, while cortisol
(a catabolic hormone) increased
when the market was variable
and unsettled. During a six-day
winning streak, the testosterone
level of one trader increased
by 74 percent. The study affirmed
what coaches have known for
years: wining triggers more
winning. Increased testosterone
produced by winning tended
to promote aggressiveness
and enthusiasm, which led
to more winning. Coaches often
schedule games earlier in
the season that will likely
result in victory. Likewise,
unexpected losses often lead
to additional losses because
of decreases in testosterone
and increases in cortisol.
Testosterone is critical for
making gains in muscle mass,
strength and overall fitness.
Bodybuilders should have winning
attitudes if they want to
make maximum gains in the
gym. (Sciences, in press;
published online April 2008)
Cell phones decrease
sperm quality
Many people seem
to have a cell phone glued
to their ear almost continuously.
A Cleveland Clinic study showed
that talking on a cell phone
impaired fertility in men.
They examined sperm quality
in 361 men undergoing fertility
evaluation and compared it
with cell phone usage during
the day. Sperm count, motility
(movement), sperm health and
overall structure deteriorated
with increased cell phone
use. Even a small amount of
exposure (less than 2 hours
per day) caused sperm cell
deterioration compared to
men who did not use cell phones.
Other studies found that talking
on a cell phone close to bedtime
could make it more difficult
to fall a sleep. Exposure
to electromagnetic radiation
from using cell phones before
bedtime caused insomnia, headache
and confusion. It appears
that radiation from cell phones
might interfere hormones and
influence many aspects of
body function. Before you
throw away your cell phone,
a six year long British study
showed that cell phones posed
no short-term risk to the
brain. However, there is enough
negative information about
cell phones to limit their
use. (Fertility and sterility,
89: 124-128, 2008; Bioelectromagnetics,
29: 185-96, 2008)
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